The plant-derived polyphenol resveratrol probably accounts for many of the beneficial effects of the “French Paradox”, in which high-fat diets fail to product devasting effects when red wine is consumed.
Most of resveratrol’s benefits have traditionally been ascribed to its powerful antioxidant and anti-inflammatory effects.
Emerging research now shows that resveratrol also stimulates cells to behave as if they had been exposed to calorie restriction, the most powerful life-extending approach shown.
Through its action on potent cellular-regulating proteins called sirtuins, resveratrol mimics calorie restriction, stimulating healthy cells to survive and diseased cells to die in an organised fashion.
Resveratrol-mediated sirtuin activation is now understood to be responsible for many of the health benefits associaited with resveratrol supplementation, including protection from age-associated disorders like cardio-vascular disease, metabolic syndrome, neurodegenerative disorders and cancer.
Drug companies are rushing to exploit the new findings about resveratrol by turning it into a drug – but highly active supplements are already available, and the existing findings on the anti-ageing properties of this substance are all based on the use of this natural product.
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