Support Prostate Cancer Awareness Week

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Prostate cancer is now the most common cancer diagnosed in men in the UK – every hour at least one man dies from this disease.

It is a cause that has suffered from years of neglect, so plan NOW for Prostate Cancer Awareness Week, 10-16 March 2008 – it’s your chance to make a difference.

Prostate Cancer Awareness Week 2008 aims to raise the profile of prostate cancer among the public and in the media. Hundreds of individuals and groups across the UK will join forces to help raise awareness of prostate cancer and raise vital funds to improve research, information and support services for men and their families who are affected by this disease

An early diagnosis of prostate cancer could improve a man’s chances of finding a successful treatment, yet 90% of adults in the UK do not know what the prostate gland does and the crucial role it plays in a man’s sexual function.

About Prostate Cancer Awareness Week

Prostate Cancer Awareness Week is an annual health awareness campaign organised by The Prostate Cancer Charity.

Every year nearly 35,000 men are diagnosed with prostate cancer in the United Kingdom and 10,000 men die from it.

African Caribbean men are three times more likely to be diagnosed with prostate cancer than their white counterparts.

The Prostate Cancer Charity is striving for a world where lives are no longer limited by prostate cancer. The Charity is fighting prostate cancer on every front – through research, support, information and campaigning.

If you have any queries about prostate cancer call The Prostate Cancer Charity’s confidential helpline 0800 074 8383 which is staffed by specialist nurses and open from 10am to 4pm Monday to Friday and Wednesdays from 7 – 9pm.

If you want to make a donation to The Prostate Cancer Charity call 0208 222 7622 or visit www.prostate-cancer.org.uk

For further information contact: Lilas Allen or Nikki Nagler on 020 8222 7653/7670. Out of hours contact: 0798 432 5001. Email: or Email Nicola.Nagler@prostate-cancer.org.uk

Will the first immortal be born in 2008?

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London: Some scientists believe that therapies to extend lifespans will be available to those born in 2008.

One such scientist is the UK’s Aubrey de Grey, a Cambridge researcher and expert in anti-ageing therapies, who believes that there is a 50% chance that rejuvenation therapies — that can delay ageing — would be developed by 2040.

This would mean that those born in 2008, who would be in their early 30s by then, would be able to use the latest therapies to defy ageing.

Eventually there would come a time, says de Grey, when ageing would become a dispensable act and finally, it would be possible to eliminate ageing from the human system altogether.

Although researchers are working to make that day a reality, immortality, as and when it happens, won’t be an overnight process. Instead, it will be a step-by-step process. For instance, initially there will be treatments that repair molecular and cellular damage so that we can continue to live another decade or two, following which we get the treatment again to remove the new damage, and so on. With new advances, these treatments will become more effective and lifespans will continually get elongated. However, immortality would not necessarily denote invulnerability.

Disease, accidents and natural disasters would all take their toll. Also, a future where death is indefinitely delayed would bring its own set of problems, like over-population, for instance. In spite of all this, the promise of beating death is one that is greatly alluring, and one that is propelling anti-ageing researchers towards their goal.

If scientists are able to manage a breakthrough, even a few decades from now, it would clearly mean that children of the future would be born with a definite advantage — of being in a position to delay death as long as they want to. And be almost immortal.

Longevity pill nearer, say scientists

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New York: Scientists are a step closer to producing a superdrug to extend lifespan, according to a report in the journal Nature.

In the journal, the researchers from Harvard report that three compounds invented by Sirtris, a pharmaceutical company, have succeeded in activating cellular defenses that slow diseases of ageing in the same way associated with resveratrol, a naturally occurring chemical found in red wine.

The difference is that Sirtris’s synthetic compounds are 1,000 times as potent as the resveratrol in wine. This solves a big drawback with the naturally occurring chemical—wine contains such minute quantities that a person would have to drink hundreds of bottles a day to see any significant benefit.

The potent new pills mimic resveratrol in mice by activating the SIRT-1 gene, which appears to trigger a process called caloric restriction. In many organisms, that process acts to slow down aging and ramp up cellular defenses in the face of a reduced diet during times of scarce food supplies. Sirtris’s new compounds, however, act without the little critters having to reduce their diet.

In past experiments, many of them conducted by Harvard pathologist and Sirtris cofounder David Sinclair, resveratrol has increased the lifespan of mice up to 24 percent, and other simpler organisms such as yeast up to 59 percent. In November 2006, Sinclair and Sirtris scientists that resveratrol could reduce the impact of a high fat diet, increase stamina two fold and significantly extend lifespan of mice.

Skeptics have long claimed that aging is too complex to be regulated by a small number of genes, though Sinclair and other leading longevity scientists such as Leonard Guarente of the Massachusetts Institute of Technology and Cynthia Kenyon of the University of California at San Francisco keep refining and supporting their argument that it is.

Investors have believed the Sirtris story enough to pony up $103 million in private rounds and $63 million in an IPO last May. Sirtris’ stock today has risen as much as 6 percent—roughly twice the rise in the S&P 500 index.

The current paper does not target longevity specifically, but demonstrates that Sirtris’s pills may slow a major disease of aging, diabetes type II, which afflicts 18 million Americans.

The pills improved insulin sensitivity, lowered plasma glucose levels, and increased the function of mitochondria, the powerhouse of the cell that is associated with healthy and long-living cells.

Sirtris recently started human trials using a super-potent version of resveratrol, and so far the drug is reported to be producing positive results. The synthetic compounds are both more potent and more stable chemically.

They also are better candidates for Food and Drug Administration approval since in many cases a synthetic compound concocted in a lab can be more consistently manufactured and standardized for doses than products based on a natural compound.

The three “New Drug Entities” described in today’s paper will begin human trials in the first half of 2008.

Longevity accelerating, says new research

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London: Longevity is accelerating and there are more 100 year olds than ever before, according to a new report by the Cass Business School.

They say that men born in 1985 can expect to live to an average age of 91, according to a new forecast of life expectancy which concludes that all existing projections are too low.

The Government’s key forecast for longevity, which is also used in the pensions and life insurance industry, has seriously miscalculated how long men will live in the future, they also say.

Life expectancy is currently 76.6 years for men and 81 for women. The new research suggests that life expectancy for men born in 1985, who turn 65 in 2050, could be as high as 97 under the most optimistic scenario, although 91 is its central forecast. That is six years higher than the Office for National Statistics’ projection. The new Cass model has been applied only to men so far, but the next phase of the research will cover women.

The new calculation has serious implications for the Government and the pensions industry, who face having to pay an extra £160,368 per person in state benefits and occupational pensions, Cass calculates.

David Blake, director of the Pensions Institute at Cass Business School, said: “Our calculations demonstrate that longevity is accelerating far beyond what is currently predicted, and there is considerable uncertainty surrounding future life expectancy. This will present a huge challenge for long-term healthcare providers and intensifies the problems faced by both government and the pensions industry. They need to update the projections they use before the pensions deficits reach catastrophic proportions.”

Professor Blake said that the Office for National Statistics had a history of underestimating new trends: “It completely underestimated the scale of the postwar baby boom, which had serious implications for the provision of schools and hospitals, and it has continually underestimated longevity of elderly people.”

The Government has voiced concerns about the ageing population and has taken some steps to make provision for more older people. The retirement age is rising from 65 to 68 by 2044. Those actions were promoted by the ONS forecast that the proportion of over65s will go from 15 per cent now to 25 per cent by 2050. However, less provision for the older population has been made in healthcare.

The new centurions

– There are about 9,000 men and women over the age of 100, but the numbers are rising by 7 per cent a year

– By 2050, more than 150,000 people will be centenarians

– The costs of treating dementia and caring for sufferers have been calculated at £17 billion (and rising) per year

How to look to look younger – the experts reveal all at our exclusive event in London’s Harley Street

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London: ELIXIR is pleased to invite you to the first of of several exclusive events in the UK and elsewhere in which you will hear from leading experts on the latest procedures and techniques in aesthetic rejuvenation and healthy ageing.

When: 25 November 2007
Where: HB Health 48 Harley Street, London W1.
Time: 10.30am to 4pm

This event allows you unique access to top professionals in cosmetic surgery, dentistry and aesthetics – so that you can ask them your questions and concerns. Many will also be offering significant discounts on treatments for those who sign up on the day.

This first event is rather special as the proceeds of the entry ticket will go to the cancer charity of the Honorable Order of Ancient Freemasons, the New Blues (UK registered charity no 1007693). The £20 ticket also includes a buffet lunch, refreshments and a goody bag.

The programme includes the following:

John Moran RD, MBBS LDSRCS, DPsSc, DFFP, Msc Nutri.Med The Holistic Medical Clinic who will discuss hormones, ageing and the menopause

Laresse – the latest non-surgical facial filler from the US. Read more about Laresse at www.laresse.com

Dr Nijon Eccles The Chiron Clinic of the Chiron Clinic at 48 Harley Street, London W1 on breast health and nutrition

Dr Daniel Sister of Beauty Works West on Carboxy Therapy – how carbon dixoide can rid you of wrinkles, flab, scars, stretch marks and more…
Dr Nigel Agger of The Harley Dental Implant Centre on cosmetic dentistry including the latest whitening techniques, veneers and implants for facial rejuvenation.

Shenaz Shariff of the Face and Body Clinic on alternative ways of removing unwanted hair and facial rejuvenation with Revitale

Restoring youthful facial volume with the deep tissue filler Sculptra by Angelica Kavouni of Cosmtic Solutions in London’s Harley Street. Visit www.cosmetic-solutions.co.uk

and

Are food allergies making you fat? More information at ALCAT food intolerence testing at www.thevitalityshopuk.com

Please note: The programme may be subject to change.

To obtain tickets email us at Club Elixir

Diabetes link to dementia

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New York: There could be a link between an adult’s diet and their risk of developing dementia, according to a newly published article in the Annals of the New York Academy of Sciences.

Individuals with diabetes are believed to be particularly susceptible to reduced cognition in old age and an unhealthy diet is known as a significant risk factor for the increasingly common condition. Eating less fattening foods and maintaining a healthy weight can help people avoid diabetes and therefore should mean they are less at risk of losing cognitive capacity in later life, the authors of the recent study suggest.

Boosting our brainpower – how far should we go, ask doctors?

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London: How many healthy people would take prescription drugs or go through an invasive medical procedure to improve their memory, concentration and other cognitive abilities?

In a thought-provoking discussion paper launched this week by the BMA, doctors discuss the ethics of healthy people seeking to improve their cognition and mental performance with pharmaceutical products or even ‘medical operations’ to help their brains perform better.

The paper ‘Boosting your brainpower: ethical aspects of cognitive enhancements1’ has been produced by the BMA’s Medical Ethics Committee (MEC) to stimulate public debate on this issue.

Chairman of the BMA’s MEC, Dr Tony Calland, said today:

“This is a fascinating area that has not been debated by the public. On the one hand, it may all seem very harmless – how many of us take omega 3 supplements to prevent memory loss? On the other hand, we need to consider where this search for optimum brain performance will lead. Should drugs or medical procedures that are designed to treat medical conditions be used by healthy people who simply want to be better than normal?

“We know that there is likely to be a demand by healthy individuals for this ‘treatment’. However given that no drug or invasive medical procedure is risk free, is it ethical to make them available to people who are not ill? Also, how much brain power is enough? There is a concern that there may be undue pressure, perhaps from employers, to ensure that workers are even more effective and productive. The BMA does not have the answers to these questions but we think it is very important that the issues are debated.”

The BMA paper examines the effectiveness of various methods that have been suggested as possible cognitive enhancers, including:

Nutrition and nutritional supplements – for example omega 3 supplements.
Pharmaceutical products – for example drugs that are used to treat attention deficit hyperactivity disorder or Alzheimer’s disease.
Brain stimulation and neurotechnology – involving techniques such as transcranial magnetic stimulation (which has been referred to as “botox for the brain”) where magnetic pulses are used to stimulate particular areas of the brain or deep brain stimulation (which has been referred to as ‘brain-lifts’) – an invasive procedure involving the insertion of electrodes into the brain that transmit tiny electrical currents. There is at the moment no evidence that these procedures can improve cognition in healthy people, but the possibility cannot be entirely ruled out. It should be remembered that people are willing to endure major surgery to enhance their visual appearance, so they may be willing to do so to improve their cognitive ability as well, if the techniques prove to be effective.

The paper discusses the balance of benefits and harms related to cognitive enhancements. There may be individual benefits, in that a person might feel better in themselves and also positional benefits, for example, the modern-day UK is highly competitive with children judged from a young age on the basis of success in tests and exams and so individuals with a competitive edge may do better than others.

Harms include the side effects of taking prescription drugs long-term. The effects on healthy people of taking these drugs may be very different from someone taking them who has a medical condition that requires treatment.

There could also be unintended consequences, for example, our brains selectively filter out some information and memories, particularly those that are trivial or traumatic, and we do not know whether drugs to enhance memory will impair this important function. There may be a risk of ‘over-enhancement’ and someone could be plagued by unwanted and traumatic memories that cause distress or even psychological harm.

We need to consider how, as a society, we should respond to the promises and challenges of cognitive enhancements, says the report. The BMA hopes that the publication of this paper will begin a public debate on this issue and, to start the process, the Royal Institution of Great Britain is holding a public meetingin London on this issue on Wednesday 14 November at 7pm.

The BMA paper ‘Boosting your brainpower: ethical aspects of cognitive enhancements’ can be accessed on the BMA website at : < ahref="http://www.bma.org.uk/ap.nsf/content/CognitiveEnhancement2007">BMA

World’s oldest creature may hold key to longevity

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Bangor: British scientists have found a 400 year-old clam, believed to be the world’s longest-living animal, off the coast of Iceland.

The scientists, from Bangor University in Wales, say that the discovery of the quahog clam, aged between 405 and 410 years old, might allow them to get a better understanding of the ageing process, as well as revealing the secrets of long life.

The creature was nicknamed Ming, after the dynasty which ruled China at the beginning of its life.

“When this animal was a juvenile, King James I replaced Queen Elizabeth I as English monarch, Shakespeare was writing his greatest plays – Hamlet, Othello, King Lear and Macbeth – and Giordano Bruno was burnt at the stake for espousing the view that the Sun rather than the Earth was the centre of the universe,” they say in a press release.

The scientists calculated the age of the animal by counting annual growth rings on the shell, a technology similar to that used when estimating a tree’s age.

According to the Guinness Book of Records, before Ming, the longest-lived animal was a clam found in 1982, aged 220.

Stroke the silent killer – new guide for victims and carers

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Are you at risk from the the third leading killer of young and old alike?

Discover a life transforming view of life after stroke, and discover new and beautiful ways to improve the quality of your life, even in the face of adversity…

Have you already suffered a stroke, or witnessed the struggles of a family member that has suffered, and want supportive, helpful and encouraging information that will allow you to lead an improved quality of life?

Every year for thousands of people stroke becomes a silent killer. For those lucky enough to survive, life following a stroke can be filled with pain, sorrow and feelings of loss and abandonment.

Fortunately, there are ways to overcome those feelings and limitations, and discover a new independence; one that you will discover is rich and rewarding.

Each year thousands of people become victims of stroke but can fail to recognize the early warning signs…

• Sudden weakness in your arm, leg or hands.
• The impression that you are not able to feel one side of your face or body.
• Difficulty seeing or experienced temporarily blurriness from one eye.
• Difficulty walking or experiencing balancing problems.
• The worst headache of your life…

If you have experienced one or more of the symptoms above, your life may be at risk. Stroke is increasingly prevalent in modern times. Call your doctor immediately or visit the nearest ER!

The impacts of stroke can be devastating for the more than
700,000 people that suffer from stroke each year.

The good news is when armed with knowledge and information; you can learn to lead an extraordinary life even following a devastating stroke. One of the most important desires stroke survivors have is the ability to regain an independent lifestyle.

How is this achieved? It is often achieved through rehabilitation, support and counselling, as well as caring for one’s individual health related problems following a stroke.

“The only work that will ultimately bring any good to any of us is the work of contributing to the healing of others…“
Adapted from M. Williamson

Friends and loved ones can also find they are confused about how to cope with a loved one’s loss. Fortunately, there is help and guidance just a moment away. Everyone can learn to heal others and heal their own sense of loss by learning more about life following a stroke.

“Life After A Stroke” is a moving, tell-all guide that teaches survivors, caregivers and close family how to cope with the after effects of a stroke. Using this guide you can learn how to regain some of your independence and improve the quality of your life to the greatest extent possible. It is available in standard and mp3 format for your convenience.

Imagine what your life would be like if you could learn to communicate with others in a sensible, logical and non-frustrating manner after a stroke…

While you may not return to the state of health you were in before, there is much evidence suggesting with proper knowledge and information, you can lead a rich and rewarding life after a stroke.

Are you ready to take back your life, or help another to do so?

Perhaps you are a caregiver looking for guidance and support while caring for a family member or loved one suffering from stroke. No matter the case, you’ve landed in just the right place to find the information you need.

Introducing a Revolutionary New Approach To Healing…Find out how to
improve the quality of YOUR life and that of your loved ones,
by adopting a few simple, common-sense strategies.

In this unique and gentle approach to Stroke, learn everything there is to know about stroke whether a survivor, friend, family member or caregiver.

This important guide contains information that will:

• Educate you about the immediate after – effects of stroke, so you know what to expect and how to overcome setbacks in the early weeks following a stroke.
• Teach you how to set goals following a stroke that will speed the progression of your healing.
• Help you understand what rehabilitation is all about, including what forms of rehabilitation are available and how they can improve your quality of life and standard of living.
• Help you discover and learn new and innovative tools for treating the physical symptoms of stroke, including spasticity and muscle pain.
• Tell you about new ways of treating old problems, including use of a popular cosmetic procedure that may reduce muscle tightness and help improve coordination and balance.
• Teach you what ITB therapy is and how it can improve delivery of targeted medications to your system, so you feel better faster, longer.
• Show you how to set up an individual approach to rehabilitation that aligns with your personal needs, goals and interests.

Learn how to avoid future strokes

Someone who has had a stroke is almost twice as likely to experience another. Learn the 2 most important steps you can take to prevent future strokes and enhance your odds for an improved quality of life following stroke.

Friends, Family and Caregivers

Friends, family and caregivers also need support and guidance during the period of time following a stroke. The good news is in Life After Stroke, you can learn how to communicate and reevaluate each member of a household’s roles, so everyone enjoys an improved quality of life when caring for a loved one.

Most importantly, Life After Stroke offers hope for the future. When you have nowhere else to turn, you always have hope.

You can find more information here: www.intrepreuner.ws

Rejuvenate and relax at the Body Beautiful Show London – free tickets from Restylane

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When was the last time that you did something just for you? When was the last time you were really pampered? Well, the time is now as The Body Beautiful Show is back on 2nd – 4th November 2007 and will give you the perfect opportunity for some you time. A luxurious, pampering day out, and a show, which demystifies the world of cosmetic treatments, Body Beautiful is a one stop authoritative, responsible guide to age defying and beautifying.

One exhibitor at this year’s Body Beautiful Show at the Business Design Centre Islington, London, is Restylane.

Restylane offers the complete solution for holding back the years and revitalising your looks naturally by smoothing away tell tale ageing lines. Restylane has the additional advantage of improving skin elasticity. Restylane treatment is quick, taking less than half an hour. The effects can be seen immediately and last from around six to nine months. Discover more about new Restylane Vital a new treatment development in skin rejuvenation, introducing the concept of moisturising from within to improve skin tone and elasticity to reverse the skin ageing process. It is great for treating veiny backs of hands, plumping the skin to reduce their appearance and smoothing the skin to make it appear less crêpey and sun damaged.

Prize:
Restylane is giving you the chance to win a pair of tickets to this year’s Body Beautiful Show at London’s Business Design Centre.

To win, all you need to do is answer the following question:

How long does Restylane last?
a) 6 – 9 weeks
b) 6 – 9 months
c) 6 – 9 years

Email your answer to us at readeroffer@elixirnews.com by 29 October 2007

For further information visit the website on www.bodybeautifulshow.co.uk

For more information on Restylane visit www.restylane.co.uk or call 0800 015 5548 to find a Restylane clinic in your area.

More 100 year olds than ever before

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London: The number of people living past 100 in England and Wales reached almost 9,000 last year for the first time, figures show.

The Office for National Statistics (ONS) said the number of centenarians had increased ninety-fold since 1911 when there were only 100 in the country, according to estimates.

The rise is being attributed to dramatic improvements in healthcare and housing conditions over the past century which have have led to people living longer.

While the number of women surviving past the landmark birthday still far outnumber men, the gap has narrowed slightly in recent years, the figures show.

The ONS calculates that there were seven women over 100 for every man in the same age group last year, compared with a ratio of eight to one four years before.

The figures, calculated from mortality rates and other factors, estimate that there were 8,970 people over the age of 100 in England and Wales last year – up from 8,340 in 2005.

The rate at which the number of people in the 100-plus age group has grown has quickened in recent years.

The 7.5% rise last year compares with an average rate of 5.8% for most of the current decade.

The ONS said that before 1940, the average annual increase was 1.9%.

While that rate picked up to 6.4% after the Second World War, it later slowed between 1981 and 2001 – partly as a result of the effects of the First World War and the 1918 flu pandemic on the population.

Why calorie restriction prolongs life

Chicago: Scientists have already proven that calorie restriction – but not nutrients – can prolong the lives of everything from yeast to mice and monkeys, but they didn’t know why, until now.

In a new study published in Cell magazine, US researchers suggest that the link between food restriction and longevity may be a molecular response to the stress from cutting back calories.

That reaction preserves critical cellular functions, helping the body to fight off age-related diseases.

In laboratory experiments on human cells, investigators found that cutting calories, while preserving the nutrients they need, starts a chain reaction in the mitochondria – or power houses of the cell – that results in the build-up of a coenzyme called NAD (Nicotinamide adenine dinucleotide).

This in turn amps up the activity of enzymes created by two genes called SIRT3 and SIRT4. The effect of all this is to strengthen the mitochondria, increase energy output and slow down the cell’s ageing process.

David Sinclair, a molecular biologist at Harvard Medical School who worked on the study commented: “We’re not sure yet what particular mechanism is activated by these increased levels of NAD, and as a result SIRT3 and SIRT4.

“But we do see that normal cell-suicide programs are noticeably attenuated,” he said, referring to the way cells are programmed to die as part of the aging and regeneration process.

“This is the first time that SIRT3 and SIRT4 have been linked to cell survival,” he said.

The fortification of the mitochondria in response to the stress of a much lower-calorie diet can help ward off diseases associated with ageing.

Damaged or dysfunctional mitochondria have been implicated in Alzheimer’s, stroke, heart disease and diabetes. It is thought that the common link is oxidative stress which damages the mitochondrial DNA leading to cell death.

Even given the growing recognition about the importance of the mitochondria in sustaining health, the researchers were surprised to find just how critical the so-called “battery packs” are to the life of the cell.

Specifically, they found that even when all the other energy sources in the cell, including the nucleus, are wiped out, the cell remains alive if the mitochondria are kept intact and functional.

“Mitochondria are guardians of cell survival,” said Sinclair. “If we can keep boosting levels of NAD in the mitochondria, which in turn stimulates buckets of SIRT3 and SIRT4, then for a period of time the cell really needs nothing else.”

Sinclair said the genes could be promising drug targets for diseases associated with ageing.

Americans die younger, reveals new report

New York Americans are living longer than ever, but still die younger than people in some 40 other countries.

Ugovernment statistics released yesterday show American life expectancy at an all-time high of nearly 78 years. The information is from 2005, the latest year for which information was available.

The Centers for Disease Control notes that death rates declined for eight of the 15 leading causes of death. These include heart disease and cancer, the two leading causes of death in America, which account for more than half of all deaths each year.

But the United States continues to slip in international rankings of life expectancy, lagging behind 41 countries including Japan, Jordan, Macau and Singapore, as well as most of Europe.

Independent researchers say America’s poor showing compared to other industrialized democracies results, in part, because of widespread obesity and a lack of health insurance.

World’s oldest person celebrates 114th birthday

Sharpeville: The world’s oldest person – 114-year-old Edna Parker – celebrated her feat of longevity on Thursday(August 16,2007)by munching on a slice of her favorite cake after telling reporters she’s amazed that she’s lived for so long.

Parker, who has outlived her husband, children and siblings, became the world’s oldest known person with Monday’s death of Yone Minagawa, a Japanese woman four months her senior.

Her life spanning three centuries began April 20, 1893, in a year that witnessed Lizzie Borden’s acquittal in the ax murders of her father and stepmother and a financial crisis called the Panic of 1893 that led to a stock market crash.

Dressed in a pink polka-dot dress and costume pearl jewelry, Parker was wheeled before television cameras and reporters Thursday in a dining room at the central Indiana nursing home where she lives.

“You’re the oldest person in the world still living, Grandma. That’s remarkable, isn’t it?” Parker’s granddaughter-in-law, Charlene Parker, asked in a loud voice.

Parker shook her head in amazement, clutching two old photographs, one an early 1900s image of her posing with one of her sisters, both of them wearing large frilly hats.

“It’s hard to believe,” she said.

Although she never drank alcohol or tried tobacco and led an active life, Parker offered no tips Thursday for living a long life. Her only advice to those gathered was: “More education.”

Parker, who attended nearby Franklin College, graduated with a teaching certificate in 1911, the same year she wed her childhood sweetheart, Earl Parker.

She taught for a few years in a two-room schoolhouse, but as was the custom of that era, her teaching career ended with her marriage. Parker traded the schoolhouse for life as a farmer’s wife, preparing meals for as many as a dozen men who worked on her husband’s farm.

Parker recalled her chores helping maintain the family’s barn, how she butchered chickens for Sunday post-church supper and noted with pride that she and her husband were one of the first owners of an automobile in their rural area.

Her ranking as the world’s oldest living person was confirmed by the Gerontology Research Group, an Inglewood, Calif.-based organization that tracks and verifies the ages of supercentenarians – people 110 or older.

L. Stephen Coles, a professor of computer science at UCLA who co-founded the group, said its researchers typically require three independent, dated pieces of documentation, such as a birth certificate or baptismal papers, to verify their ages.

The group, which is a consultant for the Guinness Book of World Records, needs a rigorous validation process, he said, because some families have exaggerated a relative’s age or faked documents, hoping for financial gain.

As of Thursday, its Web site listed 76 living supercentenarians, with Parker at the top.

“We find that these people have one thing in common, which is the longevity of their families – their parents and their siblings all were long-lived,” Coles said. “So its in the genes. They have all inherited a very lucky roll of the dice.”

That’s the case for Parker. Her sister, Georgia, was 99 when she died last year, while her sister, Opal, lived to be 88.

Parker and her husband, who died in 1938 when she was 45, had two sons, Clifford and Earl Junior. After her husband’s death, she never remarried, busying herself helping Earl Junior run the farm. He lived in the farmhouse with his wife and their two children for several years.

When they moved out, Parker lived there alone for decades until she was 100.

Twelve years ago, she moved into the Heritage House Convalescent Center in Shelbyville about 25 miles southeast of Indianapolis that’s also the home of 7-foot-7 Sandy Allen, the second-tallest woman in the world. Allen did not attend Thursday’s ceremony for Parker.

Parker currently has 5 grandchildren, 14 great-grandchildren and 13 great-great grandchildren. The youngest of them, 7-month-old Kole Scott, sat on her lap Thursday as she and her visitors ate white cake, her favorite, decorated with sugar flowers and icing declaring her “the oldest person in the world.”

Before she sampled the cake, Parker thanked her departing visitors, some of whom had attended her 114th birthday party last April.

“I want to thank you people for giving up your time and coming back. I enjoyed being with you,” she said.

Grandson Don Parker, 58, said he’s proud of his grandmother, even if she herself isn’t overwhelmed by her achievement.

“We think it’s amazing, a little lady from the country who really doesn’t care much about being acknowledged or anything like that,” he said. “She’s never really done anything special, but this comes up and she’s getting worldwide notoriety.”

Blood pressure drug increases longevity in elderly

London: An international trial looking at the benefits of giving blood-pressure lowering medication to elderly patients has stopped early, after researchers observed significant reductions in overall mortality in those receiving treatment.

The 3,845 patient Hypertension in the Very Elderly Trial (HYVET) is the largest ever clinical trial to look at the effects of lowering blood pressure solely in those aged 80 and over. Preliminary results of the trial, which is coordinated by scientists from Imperial College London, suggest that lowering blood pressure significantly reduces both stroke and mortality in the over-80s.

A number of earlier trials had demonstrated that reducing blood pressure in the under-80s reduces stroke and cardiovascular events. However, previous smaller and inconclusive studies also suggested that whilst lowering blood pressure in those aged 80 or over reduced the number of strokes, it did not reduce, and even increased, total mortality.

Patients with high blood pressure from across the world were randomised for the double-blind, placebo-controlled trial, which began in 2001. Patients were given either the placebo or a low dose diuretic (indapamide 1.5mg SR), and an additional ACE inhibitor (perindopril), in tablet form once a day.

Emeritus Professor Chris Bulpitt, HYVET Principal Investigator from the Care of the Elderly Department at Imperial College London, said: “It was not clear prior to our study whether the over-80s would benefit from blood pressure lowering medication in the same way as younger people.

Our results are great news for people in this age group because they suggest that where they have high blood pressure, such treatment can cut their chances of dying as well as stroke.”

The Steering Committee of HYVET accepted on 12th July 2007 the recommendation of its Data Safety Monitoring Board that the trial should be stopped.

Definitive figures will not be available until all the data has been collected. Results will then be published in the peer reviewed scientific press.

Over the next few months all HYVET patients will be seen for a final visit, where all patients on trial medication will be offered the option of switching to active indapamide 1.5 mg SR based antihypertensive treatment. Prior to their final visit, all patients are advised to stay on their existing drugs until they see their trial physician.

HYVET was co-ordinated by scientists from Imperial College London, working with colleagues around the world. The main trial was funded by both the British Heart Foundation and by the Institut de Recherches Internationales Servier.

1. About stroke and high blood pressure

* Stroke is the third most common cause of death in the England and Wales. In 2004, 11% of deaths amongst those aged 75-84, and 14% of deaths amongst those aged over 85 were due to stroke, according to the Office of National Statistics.

* In the UK about 150,000 people suffer a stroke each year, the equivalent of 1 every 4 minutes.

* About one third of stroke patients die within 6 months of the event, the majority occurring in the first month.

* Disability after stroke is the most important single cause of severe disability of people living in their own homes.

* There are 2 types of stroke:

a. Haemorrhagic – caused by blood leaking into brain tissue from a
blood vessel within the brain
b. Ischeamic – caused by a clot occluding a blood vessel, resulting in
loss of blood supply to a part of the brain and subsequent damage to brain tissue.

High blood pressure increases the chance of both a blood vessel leaking or rupturing, and of a clot forming within a blood vessel. High blood pressure increases the likelihood of damage to the lining of the blood vessel, which in turn leads to an increased chance of spontaneous clot formation within the blood vessel.

* The over 80s are the fastest growing group in the population worldwide – in the UK currently they account for 4% of the total population and this is expected to rise to over 11% by 2050.

* The risk of stroke increases with age, with some estimates suggesting that the risk doubles every decade after a person reaches 55 years of age

* In the UK approximately 4% of the total National Health Service budget is spent on stroke services each year.

Scientists prolong the life of mice

Madrid: Researchers in Spain discovered a way to make mice live up to 16% longer – equivalent to an extra 12 years on the average human lifespan.

Mice with elevated levels of a protein called p53 appeared younger, healthier and were more resistant to the development of cancers, according to a study by scientists at the Spanish National Cancer Research Centre.

Their discovery will accelerate the development of new drugs that fight cancer while extending healthy youth and lifespan. The protein p53 is known as “the guardian of the genome” because it makes sure that damaged cells destroy themselves and do not divide uncontrollably to cause tumours.

Scientists have long speculated that boosting our body’s levels of p53 could help us live longer, but early studies found it actually accelerated ageing.

But not according to the findings of Dr Manuel Serrano, of the Spanish National Cancer Research Centre. His team genetically engineered mice to have an extra copy of p53 and a related gene – ARF.

They showed that mice with an increased dose of the two proteins were more resistant to the development of cancers. It came as no surprise, therefore, that these animals had an extended lifespan compared with normal mice.

But remarkably, the animals outlived their normal counterparts even after the impact of having less cancer was removed from the equation, according to the study which is published in the magazine Nature.

Moreover, various biological and molecular markers of ageing indicated that these mice stay younger for longer. The researchers conclude that boosting the body’s ARF/p53 activity provides an anti-oxidant effect, which not only suppresses cancers, but also delays ageing.

Dr Serrano said: “The mice lived 16% longer in their average lifespan,” said Dr Serrano.

“Everyone agrees that ageing is produced by the accumulation of damaged cells. If p53 is the main quality control that eliminates such cells, then the expectation is that having more p53 mice will have a more strict quality control for cells, hence less cancer and less ageing.”

The study opens up possibilities for new drugs that delay ageing by boosting the body’s production of p53.

“There are a number of chemical compounds that have been developed by the big pharmaceutical companies and these compounds are able to boost p53 in the organism,” said Dr Serrano.

“These compounds are being tested now for their possible anti-cancer activity and hopefully in the light of our study also for their possible anti-ageing activity.”

Scientists unlock key to longer life

La Jolla, California: The day when humans could enjoy at least a partial “elixir of life”, a pill extending lifespan by up to 40 per cent, is now closer with the discovery of a “longevity gene”.

Scientists studying worms have found a gene that links eating less with longer life. This confirms earlier studies carried out over the last 70 years which have looked at dogs, mice, yeast, fruit flies and nematode worms, which have shown that a reduction in calorie intake by 60 per cent of normal, while maintaining a healthy diet of vitamins, minerals, and other nutrients, consistently prolongs life by up to 40 per cent.

That regime also reduces the risk of cancer, diabetes, and cardiovascular disease, while staving off age-related degeneration of the brain and nervous system.

Although some people are already imposing this strict diet on themselves, and primate experiments appear to back this longevity effect, it is still too early tell whether calorie restriction will have the same effect in humans.

The new research from the Salk Institute for Biological Studies in La Jolla, California, have identified a critical gene in nematode worms that specifically links eating fewer calories to living longer and why persistent hunger leads to a longer life.

Identifying this “longevity pathway” opens the door to the development of drugs that mimic the effects of calorie restriction and might allow people to reap health benefits without adhering to an austere regime that only the toughest ascetics can endure.

In a paper published in the magazine Nature, Prof Andrew Dillin and colleagues show that pha-4, a gene that plays an essential part in embryonic development of the worm, has a newly discovered function in adults – increased activity of the gene is associated with longevity in the “sweet spot” of food consumption between the extremes of harm caused by starvation and overeating.

Professor Dillin says: “After 72 years of not knowing how calorie restriction works, we finally have genetic evidence to unravel the underlying molecular program required for increased longevity in response to calorie restriction,” said Prof Dillin.

“This is the first gene that is absolutely essential and specific for the increased longevity response to dietary restriction.”

Initially, researchers thought that the effect of calorie restriction on ageing was to do with signalling pathways related to the hormone insulin but experiments by graduate student Siler Panowski in Prof Dillin’s lab suggested reality was more complex and another gene called SMK-1 was more involved in the effects of starvation, to their surprise.

The work suggests that insulin signalling and calorie restriction are independent pathways, but SMK-1 plays a role in both, said Panowski. The team studied 15 genes that could be involved with SMK-1 and found that the loss of only one, a gene called pha-4, negated the lifespan-enhancing effect of calorie-restriction in the worms.

Dramatically, when researchers undertook the opposite experiment— making more pha-4 in worms — longevity was enhanced, suggesting that this could offer a target for life extension drugs.

Detailed work showed that the gene can boost levels of proteins called SODs (superoxide dismutase) which mop up free radicals, harmful chemicals linked with ageing.

The researchers think that this may be a defence mechanism that helps the creatures tolerate starvation. The pha-4 gene is similar to those in people called Foxa transcription factors, which also have important roles during development and act later in life to regulate glucagons – hormones made by the pancreas to burn fat – and glucose levels, particularly in response to fasting. Humans possess three genes that are “highly similar” to the worm pha-4, all belonging to the Foxa family.

All three play an important role in development and then later on in the regulation of glucagon, a hormone made by the pancreas that unlike insulin increases the concentration of blood sugar and maintains the body’s energy balance, especially during fasting.

When food is in short supply, these genes may alter glucagon levels or cause other changes in hormones that are ultimately able to regulate the ageing process.

The team is now going to study these human genes to see if they react the same way as those in nematodes do when the worms are denied their favourite treat, bacteria.

Prof Dillin said that they would also test a range of drugs to see if they can find some that boost the activity of the human equivalent of the worm gene and, in theory, could boost longevity.

So far, only one other gene, called sir-2, has been implicated in the life- and health-prolonging response of the boy to calorie restriction. Increased use of the gene extends longevity of yeast, worms, and flies.

However, the link is not so clean cut because the loss of sir-2 disrupts the calorie restriction response only in some strains of yeast and has no effect on other organisms, such as worms.

Pet Longevity Guide – by Dr Carol Osborne

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The Pet Longevity Revoultion
by Dr Carol Osborne, D.V.M.
People and pets are now living longer than ever before. As owners, we naturally want our pets to live the longest, healthiest lives possible. After all dogs and cats aren’t just pets, they are cherished members of our family and for most of us, best friends. In fact, according to a recent Gallup survey the relationship we share with pets gets stronger with every passing year. Our love is so deep, and our relationship so special, that today almost 75% of us wouldn’t hand over their pets even in exchange for $1 million cash.

So, What’s Best For Pets?

Prevention and early disease detection combined with good nutrition, exercise, and proper veterinary care are the cornerstones of good health. Although the aging process is different for every animal (large and giant dog breeds tend to age faster than smaller ones) it generally begins at maturity, somewhere between one and two years of age, for dogs and between 10 and 12 months of age for cats. Most pets become senior citizens at seven. Giant dog breeds are considered seniors at age 5. Shorted lived cat breeds, like Persians, are considered seniors at age six.

How Old Is Old

To determine whether or not a pet is old, it’s important to distinguish between chronological and biological age. Chronological age is determined by the year in which your pet was born or the number of candles on your pets birthday cake. Anti-ageing medicine focuses on biological age, which is determined by how your pet looks, acts and feels.

LONGEVITY AND HEALTH

Longevity is attributed to 70% to lifestyle and 30% to genetics. Up to 90% of diseases in dogs and cats are due to the degenerative processes associated with ageing. Longevity research confirms the fact that a fresh organic diet along with optimal nutritional supplementation can deter and slow the aging process and can help your pet stay younger longer and enhances his or her life expectancy.

Backed By Decades of Research

A successful longevity program starts by supplementing your pet’s body with the critical nutrients it needs on a daily basis. Look for anti-ageing supplements, like PAAWS, specifically designed for pets that contain a scientifically proven, natural blend of vitamins, minerals, amino acids, anti-oxidants, herbs, essential omega 3 fatty acids, digestive enzymes, immune system boosters and longevity factors. They should be are synergistically balanced to optimize your pet’s health and maximize his or her longevity.

SIGNS OF AGEING IN PETS
Signs of aging occur slowly. Their detection requires your close observation and keen eye. Before beginning any supplement use this checklist to identify signs of aging in your pet. Then monitor your pet’s progress by filling out this list 30, 60, and 90 days later.

AGEING SIGNS in DOGS & CATS:
• Weight gain/weight loss
• Changes in skin, hair coat
• Excess shedding
• Changes in appetite
• Drinking more
• Increased urination
• Loss of house training and/or
Accidents in the house
• Hesitant to climb the stairs
• Limping/less mobile, stiff gait
• Harder to get up and down
• Has trouble or can’t jump in and
out of the car
• Bad breath
• Gas or indigestion after eating
• Vision and/or hearing loss
• Less interaction with family members
• Aimless wandering/ walking in circles
• Skin problems
• Excess itching
• Excess barking
• Frantic or cries when left alone
• Easily irritated
• Less enthusiastic when owners return home
• Sleeping more during the day and/ or staying awake at night
• Disoriented or confused
• Litter box problems
• Behavioral changes

TEST YOUR TEST YOUR PET IQ
True or False
1. Over half the dogs and cats in developed countries are overweight.
True False
True. An overweight pet is 15% or more above his or her ideal body weight.
2. Being 10% overweight decreases a pet’s life span.
True False
True. Being 10% overweight also predisposes pets to heart, liver and kidney disease,
as well as arthritis, diabetes and cancer.
3. It is okay to feed my pet my leftovers.
True False
False, Throw out table scraps.
4. Leave meals in your pet’s bowl all day.
True False
False, don’t free-feed. This leads to obesity.
5. Exercising an old pet is not a good idea.
True False
False. Exercise for dogs and cats (of all ages) is essential for good health
6. It is risky to put a pet on a diet.
True False
False. It is risky to let any pet stay fat.

DR. CAROL’S GORMUTT TREATS:
Recipes for Tail Wagging K-9 Treats
BOW WOW’S Blazin Biscuits

3/4 cup flour 1 tsp Vanilla extract
1/2 tsp. baking soda 1 1/2 cups regular oats (uncooked)
1/2 tsp. salt 1 cup shredded cheddar cheese
2/3 cup butter 1/2 cup wheat germ
2/3 cup brown sugar 1 cup bacon, cooked crisp &
1 cup bacon, cooked crisp 1 egg (slightly beaten)

Combine flour, baking soda, and salt. Mix well and set aside. Cream butter and brown sugar. Beat in one egg and vanilla. Add flour mixture, stirring well. Stir in cheese, wheat germ and crumbled bacon. Drop dough by rounded tablespoons onto un-greased baking sheet. Bake at 350 degrees for 15 minutes or until golden brown. Cool 1 minute and serve!

Carol Osborne, D.V.M. is a leading authority on alternative veterinary medicine and age-related pet diseases. She is worlds only veterinarian to be a board certified Diplomat of the American Academy of Anti-Aging Medicine, and is the author of international best sellers Naturally Healthy Dogs and Naturally Healthy Cats. She is a popular lecturer and broadcaster on the subject of pet longevity and wellness has her own patented line of longevity nutritional products for pets which can be purchased at www.drcarol.com

Most Britons believe they look 10 years younger than their real age

London: Almost a third of women (31 per cent) in their early sixties believe they look ten years younger. Almost a quarter of men in their early 60s (24 per cent) believe they look 10 years younger.

The majority of people in the UK say they look and feel younger than their years. 12 per cent of women aged 36 or over believe they look ten years younger than their years and almost a third (31 per cent) say they feel ten years younger than their real age!*

The new research, compiled by innovative private medical insurer, PruHealth, reveals despite the pressures of modern life, the majority of Britons excel at holding back the years.

The Older, the Better!

Contrary to popular belief, more than half (54 per cent) of women aged 40-plus believe they look younger than they are. But it’s not just women who look and feel younger than their years, 14 per cent of men in their early 40s think they look 10 years younger than they actually are.

70 per cent of women in their early sixties feel ten years younger, and a third (31 per cent) say they look ten years younger. Similarly, almost a quarter of men in their early 60s (24 per cent) believe they look 10 years younger.

However, the optimum age for looking and feeling younger is in your 70s, with 93 per cent of women feeling younger and 84 per cent saying they look younger than their years!

Modern Living

The pressures of modern life are taking the biggest toll on men and women in their thirties, with juggling work, starting a family and financial worries impacting on this generation’s looks. 17 per cent of men and 12 per cent of women in their thirties think they look older than their years.

The findings also reveal the majority of Britons manage to stay looking and feeling youthful despite putting daily pressures on their bodies:

· Nearly one in four (23 per cent) Brits say their stress levels are eight or above on a scale of one to 10 (10 being the highest)

· 45 per cent of people have six hours of sleep or less per night

· Nearly one in four (23 per cent) adults drink more than 14 units of alcohol each week

· A fifth (20 per cent) of Brits smoke cigarettes every day

· 50 per cent of people only do moderate exercise less than once a week

Spend to Mend

For many Brits, the secret to eternal youth could be down to balanced lifestyles. Although the average person splurges nearly £50 a month (£48.13) on booze, cigarettes and junk food, we also spend £29.03 each month on fruit and veg and vitamins. Our monthly spend of £25.94 on skin, hair and body care could also be in a bid to stave off the ‘ugly’ effects of fatty foods, cigarettes and alcohol, such as bad skin and greasy hair.

Katie Roswell, Health and Lifestyle Expert, PruHealth, said: “Despite many recent warnings of bad diets and binge drinking, people in the UK are generally living balanced lifestyles and as a result are feeling and looking better than ever. If we continue to move in the right direction by eating sensibly, cutting back on smoking and making time in our busy schedules for regular exercise, hopefully we’ll be able to continue holding back the years!”

Full consumer product information can be found at www.pruhealth.co.uk

*YouGov conducted an online survey of 2,193 people for PruHealth between 20 – 23rd April 2007. Data is weighted to be representative of the GB population.

** Government Actuary Department, 2005

About PruHealth

PruHealth was launched in October 2004 as a joint venture between Prudential and Discovery Holdings from South Africa. Since launch, PruHealth has grown quickly. It now covers over 100,000 lives and in a sample of its individual customers, one third said they had changed their behaviour for the better because of its Vitality reward scheme which encourages policyholders to look after their health.

PruHealth was chosen, among other stakeholders, to champion the Department of Health’s “small change, big difference campaign.”

The campaign is aimed at adults with the message that even small changes in diet and physical activity can make a difference. Launched by Tony Blair and Patricia Hewitt in April 2006, PruHealth was the only private medical insurer to be selected at launch.

Wine drinkers live longest, says new research from Finland

Helsinki: Wine drinkers are healthier than drinkers of beer and spirits, according to new research conducted on men living in Finland. That’s not too much of a surprise considering the lifestyles associated with each of the beverage types, but the study also suggested that moderate consumption of wine may contribute to a better, longer life.

Over the course of the nearly three-decade study, wine drinkers had a lower mortality rate than drinkers of other alcoholic beverages. The study, published in the February 2007 issue of the Journals of Gerontology, sought to determine if one’s drinking habits affected longevity when measured over a long period of time.

The study was led by Timo Strandberg, a researcher at the University of Oulu, Finland. His subjects, all male residents of Finland, were all born between 1919 and 1934 and all had health checkups at the Institute of Occupational Health in Helsinki during the 1960s and 1970s. The men had their alcohol intake recorded during these examinations and were asked how they felt about their health. All of the men also had “leading positions” in private companies, which the scientists concluded came with some of the highest incomes in Finland (although exact amounts were not made available).

“This setting,” the study authors wrote, “offers a clearer test for the effects of alcoholic beverages because the influence of social class on beverage preference is decreased.”

By tracking down the men in 1974 and repeating the exam of them in 1985 and again in 2000, the scientists hoped to determine if alcohol consumption is related to both the quality–as well as the length–of life.

At the first examination, in 1974, 2,468 men reported if they preferred wine, beer or spirits, or if they didn’t drink, or if they had no particular favorite alcoholic beverage. By the time of the second stage of the study, in 1985, only 1,369 men were available to be reassessed. Some dropped out of the study, some changed alcohol habits and 93 of the men had died. There was another examination in 2000, and by the time of the final calculations, in 2002, the scientists were left with a pool of 1,127 men who consumed an average of three drinks a day or less, and who also did not change their drinking preferences over the course of the study.

“Preference of wine was associated with decreased mortality when compared with preference for beer or spirits over a follow-up of 29 years,” the scientists reported. Wine drinkers had a 34 percent lower rate of mortality, when compared to spirits drinkers, and beer drinkers had a 9 percent lower rate compared to spirits drinkers.

Wine drinkers were also in better health at the end of the study and had performed better on mental health tests. However, wine drinkers also tended to exercise more and smoke less, which leaves the researchers still with the possibility that wine is simply one piece of the happy, long-life puzzle, as opposed to a deciding factor.

“Is it the drinker rather than drink characteristics, as healthier men preferred wine?” asked Strandberg of the results. “That is what is important. The same applies for differences between beer and spirit drinkers,” he added. “Spirit preferrers may lead a more dangerous life, with more risk factors, and all hidden aspects may not be culled in an epidemiologic study.”

Is 50 the new 25 – new UK report?

London: The over 50s are living the lives of 25 year olds, according to a new report from the UK’s Future Foundation.

The second flush of youth is the result of improved health and longer life expectancy with men expecting to live 15 years after retirement and women 22.

Martin Lloyd-Elliott, a psychologist, who contributed to the report said that there had been a shift in expectations with over 50s expecting doors to open rather than close in the second phase of life. With more wealth and more free time older people are taking the time to do more with their leisure such as travel.

Unlike their predessesors who spent their time doing domestic chores over 50s now spend their time socialising and shopping. In fact over 50s spend twice as much time shopping as their counterparts did 50 years ago. They also go to the shops for longer than today’s twentysomethings.

They are also keen on keeping fit, spending the same amount of time as on sport and exercise as 25-year-olds did in 1957.

Neurotic men likely to die earlier, says new US report

Mellow men live longer, according to o new research from Purdue University in West Lafayette, Indiana in the US.

“We found that neurotic men whose levels (of neurosis) dropped over time had a better chance at living longer,” said Dan Mroczek, an associate professor of child development and family studies at Purdue

“They seemed to recover from any damage high levels of the trait may have caused. On the flip side, neurotic men whose neuroticism increased over time died much sooner than their peers.”

Researchers defined a neurotic personality as “a person with the tendency to worry, feel excessive amounts of anxiety or depression and to react to stressful life events more negatively than people with low levels of the trait.”

While researchers tracked 1,663 men — more than 90 per cent of whom were white — for 12 years, Mroczek believes the results would be similar for women or other ethnicities.

“You can find the full range of personalities in any ethnic or gender group,” he said. “There are those who are laid-back and then there are those who worry, who react very poorly to stress, who are always on edge.” Mroczek suspects a contributing factor behind early death in neurotic men may be high levels of cortisol, a stress hormone. Later this year, he will study the link.

The study’s results will be published in the Psychological Science in late May.

Pet Longevity – Carol Osborne DVM

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Dr Carol Osborne DVM is a leading authority on alternative veterinary medicine and age-related pet diseases. She is the world’s only veterinarian to be a board certified Diplomat of the Academy of Anti-Ageing Medicine and is the author of the international best-sellers Naturally Healthy Dogs and Naturally Healthy Cats.

She is also a popular lecturer and broadcaster on the subject of pet longevity and wellness and has her own line of nutritional products for pets. Web site www.drcarol.com Email your pet health concerns to her at Dr Carol Osborne

Growing elderly population will result in care shortage, warn Swiss researchers

London: The growing ageing population means that there will be a shortage of people to care for them, according to new research published in the British Medical Journal.

Many people fear that population ageing will generate a demand for long term care that will outpace the supply of formal care. So to anticipate the future long term care needs of the oldest people, researchers in Switzerland suggest introducing the “oldest old support ratio.”

Their ratio is based on four age groups – the young, those of working age, younger retired people (aged 50-74), and the oldest people (aged 85 and over) – and provides information on the number of people potentially available to care for one person aged 85 or over.

Based on current trends, they estimate that the young retired generation will have to play a greater caring role in the future.

They illustrate this by using trends in Switzerland and the United States. For example in Switzerland, the oldest old support ratio has fallen from 139.7 in 1890 to 13.4 in 2003 and the same trend applies in the US. These ratios are expected to decrease to 3.5 in Switzerland and 4.1 in the United States by 2050.

These forecasts highlight the large fall in the potential pool of informal carers, say the authors. And they warn that failure to anticipate the consequences of these expected trends today will be a mistake that will be heavily paid for tomorrow.

The use of this new ratio should help make governments realise the implications of the substantial intergenerational changes that are occurring and aid policy makers to formulate adequate policies, they conclude.

“We need to face up to the huge cost of care in both the formal and informal sector,” add experts in an accompanying editorial.

In England it is estimated that 8.5 million people provided informal care in 2000, 3.4 million of whom cared for people over 65 years. Informal care is often unseen and unmeasured and usually falls to families, but as the retirement age increases and families become increasingly fragmented, we do not know if they will be around to help, or indeed, will be willing to help. And with the crisis in pensions, there will be less money for people to buy additional care.

“First world countries have swapped infant mortality and childhood illness for the burden of care of the elderly,” they write. “Caring for the oldest old is the price of affluence.”

New Book: Trends Beyond Life – in search of immortality

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London-based trend forecaster Susan Muncey’s book Trends Beyond Life – In Search of Immortality is an extremely opportune and relevant book. The beginning of a new year is always a time to reflect on the past and, more pertinently, consider the future.

However, in this rapidly changing world where technology and science are opening new and challenging doors, where does that leave us morally and culturally? Susan Muncey assesses recent social trends affecting our daily lives, including our quest for eternal youth and immortality, which she sees as a key trend of our times. Muncey then expands on this theme and explores the ways that death and remembrance have been handled historically and analyses current developments and thinking.

‘The quest for longevity by reversing the signs of ageing and increasing life expectancy seems to have become the Holy Grail. I wanted to explore what drives us towards this desire and taking it further, what immortality actually means. Why do we wish to be remembered? How do we wish to be remembered?’ says Susan Muncey.

The book also includes in-depth research into experiences of death and bereavement in both the developed and the developing world. Muncey travelled to Zambia where she saw how the country is coping with a huge increase in mortality rates and the initiatives being made to implement changes within the burial system. Back in the UK, Muncey details how our views on death are evolving and highlights new trends in funerals – such as green burials and freeze dried cremation – and remembrance including the use of the internet as a vital tool in helping to create immortality.

‘What started as a study of trends in death turned out to be a contemplation on immortality and the many ways that we can achieve it these days,’ says Muncey.

Susan Muncey is the founder of the digital time capsule Diary of Mankind www.diaryofmankind.com where users can record their life, their wishes and their desires for future generations. Muncey also runs Visuology www.visuology.com, a trend forecasting and lifestyle coaching company. Her clients include the cutting-edge designer uniform company, nouniform. A Cambridge graduate, Susan Muncey has had a broad career ranging from working in investment management in the City to opening the late 90s cult boutique Fashion Gallery in London’s Little Venice. Costs $15.44 (£7.95, €11.70) Buy www.amazon.co.uk and at leading booksellers